Temi vs. LillyDirect: brand Zepbound, compounded tirzepatide, or both

Lilly's self-pay prices are $299 a month for 2.5 mg, $399 for 5 mg and $449 for 7.5 mg, 10 mg, 12.5 mg and 15 mg, for vials and KwikPens alike [1]. The $449 price on higher doses depends on the Zepbound Journey Program: refill within 45 days or the price rises to $499 for 7.5 mg and $699 for 10 mg and above. A month is 28 days, or four vials.

Yes. LillyDirect is a pharmacy, so a licensed prescriber has to send your prescription to LillyDirect Pharmacy [2]. If you do not have one, its site lists independent telehealth providers, noting that their quoted rates exclude medication and that Lilly does not endorse them. A Temi clinician can also prescribe Zepbound when clinically appropriate, and LillyDirect then fills it [5].

For KwikPens, yes: select insurance is accepted, and commercially insured patients with coverage may pay as little as $25 with a savings card, which excludes government beneficiaries [1]. Single-dose vials are self-pay only. Temi never bills insurance, so if your plan covers Zepbound, the insured KwikPen route through LillyDirect will almost certainly cost you less than any cash option.

It contains the same active ingredient, but it is not the same product. Zepbound is Lilly's FDA-approved medicine. Compounded tirzepatide is prepared by a compounding pharmacy and is not FDA-approved [7]. Temi offers both routes: it can prescribe branded Zepbound for LillyDirect to fill, or compounded tirzepatide from a named pharmacy. Our compounded tirzepatide vs. Zepbound page sets out the differences in detail.

For the branded drug, no: a Temi prescription for Zepbound is filled by LillyDirect at Lilly's price [5]. The saving only appears if you and your clinician choose compounded tirzepatide, which starts at $104.99 per 8.5 mg vial plus a $39 service fee [7], against $299 to $449 a month for Zepbound. Vial size and weekly dose decide how long each lasts.

On 7.5 mg and higher doses, Lilly's page says the regular price applies instead of the Journey Program price: $499 a month for 7.5 mg and $699 for 10 mg, 12.5 mg and 15 mg [1]. The 2.5 mg and 5 mg prices are not tied to that window. Temi's compounded prices carry no refill-timing condition, though a lapse in treatment is a conversation to have with your clinician.

Yes. Temi's Zepbound page says a Temi clinician can prescribe branded Zepbound when clinically appropriate and that it is filled through LillyDirect, with you paying LillyDirect's self-pay price [5]. Temi does not sell or dispense the brand and does not set that price. Submitting a request starts a clinician review; it does not guarantee a prescription.

Yes. Foundayo, Lilly's once-daily oral GLP-1, is dispensed through LillyDirect at $149 a month for 0.8 mg and 2.5 mg, $199 for 5.5 mg and $299 for 9 mg and above; the 2.5 mg and 5.5 mg prices are temporarily reduced through 31 December 2026 [3]. A Temi physician can prescribe Foundayo, but Temi does not fill it through its own checkout [6].