Cheap Probenecid Refill Online — $15 Flat Fee
Refill your probenecid online for $15. A board-certified physician reviews your request and sends the prescription to any US pharmacy you pick: CVS, Walgreens, Cost Plus Drugs, or the independent down the street. Most refills are done in under 24 hours. Currently live in California, Delaware, and Florida.
Refill ProbenecidWhat is probenecid?
Probenecid is a uricosuric medication. It lowers blood uric acid by blocking the kidney’s reabsorption of uric acid, which increases how much is excreted in the urine. It’s prescribed for chronic gout and hyperuricemia, particularly in patients whose kidneys under-excrete uric acid.
Probenecid has been used clinically since the 1950s. Common brand names are Benemid and Probalan, though most prescriptions are filled with the generic.
Probenecid is unusual among modern prescriptions in that its clinical role extends well beyond gout. The CDC’s 2021 STI Treatment Guidelines still list it as part of a recommended regimen for pelvic inflammatory disease (cefoxitin 2 g IM plus probenecid 1 g orally) and as an alternative regimen for neurosyphilis. For chronic gout, the American College of Rheumatology’s 2020 guideline conditionally recommends probenecid as an alternative urate-lowering therapy, reserved for patients with preserved kidney function and no history of uric acid kidney stones.
Temi refills probenecid for patients who already have an active prescription. We don’t start new prescriptions. Starting probenecid requires an initial workup with a physician to confirm kidney function, rule out uric acid stone history, and plan hydration.
What conditions does probenecid treat?
- Chronic gout. Probenecid is prescribed for patients whose kidneys under-excrete uric acid, typically as second-line therapy. See our gout treatment page.
- Hyperuricemia in under-excretors. Some patients produce normal amounts of uric acid but fail to excrete enough. Probenecid corrects the excretion problem directly.
Common probenecid dosages
Probenecid is supplied as 500 mg oral tablets. Dosing is titrated gradually to avoid precipitating a gout flare and to let the kidneys adapt to the increased uric acid load.
| Phase | Typical dose |
|---|---|
| Starting dose (first week) | 250 mg twice daily. |
| Maintenance | 500 mg twice daily. |
| Titration | Can be increased by 500 mg every 4 weeks up to a maximum of 2 g per day if uric acid targets aren’t reached. |
Temi refills your existing dose. If you’re already on probenecid at a stable dose, our physician can refill it. We don’t adjust doses or start new prescriptions.
What are the side effects of probenecid?
Most patients tolerate probenecid well. The most important precautions are around kidney stones and contraindications in patients with significant kidney impairment.
Common side effects
- • Nausea, vomiting, loss of appetite
- • Headache
- • Rash
- • Transient increase in gout flares at the start of therapy (uric acid shifts out of tissues)
Serious reactions: seek care
Contact a clinician if you develop flank pain, blood in the urine, unusual bruising or bleeding, fever, persistent fatigue, or a widespread rash.
Probenecid can cause uric acid kidney stones (which is why hydration matters), aplastic anemia, and hepatic necrosis. These are rare but need prompt evaluation.
Who should not take probenecid
Probenecid is not appropriate for patients with a history of uric acid kidney stones, severe kidney disease (creatinine clearance below about 30 mL/min), or certain blood disorders. Your physician will also check for drug interactions. Probenecid affects the excretion of many other drugs, including penicillins, methotrexate, NSAIDs, and some antivirals.
Monitoring while taking probenecid
Your physician typically checks serum uric acid to confirm the drug is working and monitors for signs of kidney stones. Stay well hydrated throughout therapy, aiming for at least 2 to 3 liters of water per day unless your physician has told you otherwise.
Sources: DailyMed, MedlinePlus. This page is educational and not a substitute for advice from your prescribing physician.
How Temi refills your probenecid
Complete Health Form
Takes about 2 minutes. Tell us your medication history and current dose.
Board-Certified MD Review
A licensed physician reviews the request, usually within 24 hours.
Sent to Your Pharmacy
We send the prescription electronically to whichever pharmacy you pick: CVS, Walgreens, Cost Plus Drugs, or the local independent.
How much does a probenecid refill cost?
One flat fee per refill. No subscription and no hidden charges.
- Board-certified physician review
- Prescription sent to your pharmacy of choice
- Full refund if we can’t approve the refill
Paying cash? We usually point people to Cost Plus Drugs. Generic probenecid is inexpensive and often cheaper there than at a retail pharmacy.
Which states does Temi refill probenecid in?
Temi refills probenecid online in California, Delaware, and Florida as of April 2026. We add states as we get new physicians licensed.
Alternatives to probenecid
Allopurinol is the first-line urate-lowering drug for gout and is typically preferred over probenecid because it works regardless of whether a patient is an over-producer or under-excretor of uric acid. Febuxostat is a second-line xanthine oxidase inhibitor used when allopurinol isn’t tolerated. Colchicine treats acute flares and is often prescribed alongside urate-lowering therapy during the first months of starting it. Your physician picks the combination based on your kidney function, uric acid excretion pattern, medical history, and how your current regimen is working.
- Allopurinol (Zyloprim): Refill with Temi
- Febuxostat (Uloric): Refill with Temi
- Colchicine: Refill with Temi
Temi refills any non-controlled medication you already take. Submit a request and we’ll confirm coverage before charging you.
You pick your pharmacy
Temi sends your prescription to any licensed US pharmacy: CVS, Walgreens, Walmart, Costco, Cost Plus Drugs, or the independent around the corner. You choose your pharmacy, no mail-order lock-in. Check cash prices wherever you want and route the prescription to whichever pharmacy comes out cheapest for you.
More than probenecid
Temi refills any non-controlled medication you already take. That includes blood pressure, cholesterol, thyroid, and diabetes drugs; mental health medications like Lexapro, Wellbutrin, and Zoloft; allergy and asthma maintenance therapy; and plenty more. Same $15 fee, same process, any US pharmacy.
Frequently asked questions about probenecid refills
Can I get a probenecid refill online without a new appointment?
Yes, if you already have an active probenecid prescription and you're stable on your current dose. Fill out a short health form, a board-certified physician reviews it, and the prescription goes electronically to whichever pharmacy you pick.
How is probenecid different from allopurinol and febuxostat?
Probenecid works through a different mechanism. Allopurinol and febuxostat block the production of uric acid by inhibiting xanthine oxidase. Probenecid increases how much uric acid your kidneys excrete in urine. That makes it a good fit for patients who under-excrete uric acid, but it is not suitable for patients with a history of uric acid kidney stones or severe kidney disease.
Who is probenecid prescribed for?
Probenecid is typically prescribed for chronic gout patients whose uric acid stays elevated because their kidneys don't excrete enough of it. Per the American College of Rheumatology's 2020 gout guideline, it's conditionally recommended as a second-line option when a xanthine oxidase inhibitor (allopurinol or febuxostat) isn't tolerated or doesn't get uric acid to target.
Why do I need to drink so much water on probenecid?
Probenecid increases uric acid in the urine, which raises the risk of uric acid crystallizing there and forming kidney stones. Staying well-hydrated (physicians typically recommend at least 2 to 3 liters of water per day) keeps the urine dilute. Some patients also need urine alkalinization, usually with potassium citrate or sodium bicarbonate.
What are the common side effects of probenecid?
The most common side effects are nausea, vomiting, loss of appetite, and headache. Rash and allergic reactions can occur. More serious but rare reactions include kidney stones, aplastic anemia, and hepatic necrosis.
What's the typical probenecid dose?
Probenecid is usually started at 250 mg twice daily for the first week, then increased to 500 mg twice daily. Your physician may increase the dose further (up to 2 g per day divided) if uric acid targets aren't being met. Dosing is not appropriate if your kidney function is significantly impaired.
How fast can I get my probenecid refill from Temi?
Most refill requests get a physician review within 24 hours. After approval, the prescription goes to your pharmacy electronically. If you're running low, submit the refill a few days before you actually need it.
Can Temi send my probenecid to Cost Plus Drugs?
Yes. Temi sends prescriptions to any licensed US pharmacy, including Cost Plus Drugs. Generic probenecid is inexpensive and usually cheaper at Cost Plus than at retail chains with or without insurance.
Does insurance cover my Temi probenecid refill?
No. Temi is cash-pay and doesn't bill insurance for the $15 physician review fee. Your pharmacy can still apply insurance to the medication itself. Generic probenecid is usually cheap enough that the cash price and insurance copay are similar.
In which states does Temi refill probenecid?
California, Delaware, and Florida. We add states as we license more physicians, including through the Interstate Medical Licensure Compact. Join the waitlist at usetemi.com and we'll email you when your state opens.
Reviewed by a board-certified physician licensed in California, Delaware, and Florida.
Last reviewed: April 17, 2026.
This page is educational and isn’t a substitute for advice from your prescribing physician. For questions about pricing, which states we serve, or how the flow works, see our FAQ.
Ready to refill your probenecid?
$15 flat fee. Any pharmacy. Usually reviewed within 24 hours.
Refill Probenecid