Cheap Colchicine Refill Online — $15 Flat Fee
Refill your colchicine online for $15. It’s also sold as Colcrys and Mitigare. A board-certified physician reviews your request and sends the prescription to any US pharmacy you pick: CVS, Walgreens, Cost Plus Drugs, or the independent down the street. Most refills are done in under 24 hours. Currently live in California, Delaware, and Florida.
Refill ColchicineWhat is colchicine?
Colchicine is an anti-inflammatory medication derived from the autumn crocus plant. It has been used medicinally for centuries and was FDA-approved under the modern brand Colcrys in 2009. It works by disrupting microtubule formation in inflammatory cells, which blocks the neutrophil response that drives acute gout flares.
The generic name is colchicine. Common brand names are Colcrys, Mitigare, and Gloperba (oral solution). All contain the same active ingredient.
Colchicine’s role has expanded well beyond gout. In June 2023, the FDA approved low-dose colchicine (Lodoco, 0.5 mg once daily) to reduce the risk of heart attack, stroke, coronary revascularization, and cardiovascular death in adults with established atherosclerotic disease or multiple cardiovascular risk factors, making it the first anti-inflammatory drug ever approved for cardiovascular disease. The approval was supported by the LoDoCo2 trial (NEJM, 2020), which found a 31% reduction in major cardiovascular events among 5,522 patients with chronic coronary disease on top of standard therapy.
Temi refills colchicine for patients who already have an active prescription. We don’t write new prescriptions. Starting colchicine requires an initial workup with a physician, especially because dosing needs to be individualized for kidney function, liver function, and drug interactions.
What conditions does colchicine treat?
- Acute gout flares. Colchicine is most effective when taken at the first sign of a flare. See our gout treatment page.
- Gout flare prophylaxis. Often prescribed for the first 3 to 6 months after starting allopurinol or febuxostat, since those drugs can temporarily trigger flares.
- Familial Mediterranean fever (FMF). Long-term colchicine therapy prevents attacks and reduces the risk of amyloidosis.
- Pericarditis. Used (off-label) to reduce inflammation and prevent recurrence.
Common colchicine dosages
Colchicine is most commonly prescribed as 0.6 mg tablets. Dosing depends on the indication and needs to be adjusted for kidney function, liver function, and interacting medications.
| Use | Typical dose |
|---|---|
| Acute gout flare | 1.2 mg at first sign of flare, then 0.6 mg one hour later. Maximum 1.8 mg in the first 24 hours. |
| Gout prophylaxis | 0.6 mg once or twice daily. |
| Familial Mediterranean fever | 1.2 mg to 2.4 mg daily, divided. |
Temi refills your existing dose. If you’re already on colchicine at a stable dose and indication, our physician can refill it. We don’t adjust doses or start new prescriptions.
What are the side effects of colchicine?
Colchicine has a narrow therapeutic index. The common side effects are dose-related and usually gastrointestinal. Serious toxicity is rare at recommended doses but can be fatal at high doses or with certain drug interactions.
Common side effects
- • Diarrhea (the most common reason patients stop the drug)
- • Nausea and vomiting
- • Abdominal cramping
- • Fatigue
Serious reactions: stop taking and seek care
Stop colchicine and get care if you develop muscle pain or weakness, numbness or tingling, unusual bleeding or bruising, severe vomiting or diarrhea that won’t stop, or signs of infection.
High-dose or chronic colchicine toxicity can cause bone marrow suppression, muscle breakdown (rhabdomyolysis), and peripheral neuropathy. These are most likely at doses above those labeled or when colchicine is combined with interacting drugs.
Drug interactions
Colchicine is metabolized by CYP3A4 and transported by P-glycoprotein. Strong inhibitors of either can cause dangerous buildup. Flag the following to your physician if you’re taking colchicine: clarithromycin, erythromycin, ketoconazole, itraconazole, ritonavir and other protease inhibitors, diltiazem, verapamil, and cyclosporine. Dosing usually needs to be reduced when colchicine is used alongside these drugs, and in some cases the combination should be avoided entirely.
Sources: DailyMed, MedlinePlus. This page is educational and not a substitute for advice from your prescribing physician.
How Temi refills your colchicine
Complete Health Form
Takes about 2 minutes. Tell us your medication history and current dose.
Board-Certified MD Review
A licensed physician reviews the request, usually within 24 hours.
Sent to Your Pharmacy
We send the prescription electronically to whichever pharmacy you pick: CVS, Walgreens, Cost Plus Drugs, or the local independent.
How much does a colchicine refill cost?
One flat fee per refill. No subscription and no hidden charges.
- Board-certified physician review
- Prescription sent to your pharmacy of choice
- Full refund if we can’t approve the refill
Paying cash? We usually point people to Cost Plus Drugs for reasonable cash prices on generic colchicine.
Which states does Temi refill colchicine in?
Temi refills colchicine online in California, Delaware, and Florida as of April 2026. We add states as we get new physicians licensed.
Alternatives to colchicine for gout
Colchicine treats acute flares and is also used as short-term prophylaxis. For long-term uric acid control, the drugs of choice are allopurinol (first-line) and febuxostat (second-line). Probenecid is a uricosuric alternative for patients who under-excrete uric acid. NSAIDs and corticosteroids are common alternatives to colchicine for acute flare treatment and are prescribed based on your kidney function, cardiovascular risk, and other medications.
- Allopurinol (Zyloprim): Refill with Temi
- Febuxostat (Uloric): Refill with Temi
- Probenecid: Refill with Temi
Temi refills any non-controlled medication you already take. Submit a request and we’ll confirm coverage before charging you.
You pick your pharmacy
Temi sends your prescription to any licensed US pharmacy: CVS, Walgreens, Walmart, Costco, Cost Plus Drugs, or the independent around the corner. You choose your pharmacy, no mail-order lock-in. Check cash prices wherever you want and route the prescription to whichever pharmacy comes out cheapest for you.
More than colchicine
Temi refills any non-controlled medication you already take. That includes blood pressure, cholesterol, thyroid, and diabetes drugs; mental health medications like Lexapro, Wellbutrin, and Zoloft; allergy and asthma maintenance therapy; and plenty more. Same $15 fee, same process, any US pharmacy.
Frequently asked questions about colchicine refills
Can I get a colchicine refill online without a new appointment?
Yes, if you already have an active colchicine prescription and you're stable on your current dose. Fill out a short health form, a board-certified physician reviews it, and the prescription goes electronically to whichever pharmacy you pick.
What's the difference between colchicine and Colcrys?
Colchicine is the generic name and Colcrys is a brand name. Same active ingredient, same mechanism, same effect in the body. Generic colchicine is much cheaper than brand Colcrys or Mitigare, and it's what most pharmacies dispense.
How is colchicine used for a gout flare?
The FDA-approved dosing for an acute gout flare is 1.2 mg (two 0.6 mg tablets) at the first sign of a flare, followed by 0.6 mg one hour later. Do not exceed 1.8 mg in the first 24 hours. Dosing is different if you're on certain drug interactions or have reduced kidney or liver function, so stick to what your physician has written for you.
Can colchicine be taken daily to prevent gout flares?
Yes. A common prophylactic dose is 0.6 mg once or twice a day, often prescribed for the first 3 to 6 months after starting allopurinol or febuxostat. This is because urate-lowering drugs can temporarily trigger flares as uric acid shifts out of tissues. Long-term prophylaxis is used for some patients with frequent recurrent flares.
What are the common side effects of colchicine?
The most common side effects are gastrointestinal: diarrhea, nausea, vomiting, and abdominal cramping. These are dose-related. Rare but serious effects include bone marrow suppression, muscle breakdown (rhabdomyolysis), and peripheral neuropathy, usually at toxic dose levels.
What drugs interact with colchicine?
Colchicine has serious interactions with strong CYP3A4 inhibitors (clarithromycin, erythromycin, ketoconazole, itraconazole, ritonavir) and P-glycoprotein inhibitors (cyclosporine, ranolazine). These combinations can cause life-threatening toxicity. Tell us about every medication you take when you submit your refill request, including over-the-counter drugs and supplements.
How fast can I get my colchicine refill from Temi?
Most refill requests get a physician review within 24 hours. After approval, the prescription goes to your pharmacy electronically. If you have recurrent flares, it's worth keeping a refill on hand so you're not caught without medication.
Can Temi send my colchicine to Cost Plus Drugs?
Yes. Temi sends prescriptions to any licensed US pharmacy, including Cost Plus Drugs. Generic colchicine at Cost Plus is often cheaper than the same drug with insurance at a retail pharmacy.
Does insurance cover my Temi colchicine refill?
No. Temi is cash-pay and doesn't bill insurance for the $15 physician review fee. Your pharmacy can still apply insurance to the medication itself. Generic colchicine is usually reasonably priced even without insurance.
In which states does Temi refill colchicine?
California, Delaware, and Florida. We add states as we license more physicians, including through the Interstate Medical Licensure Compact. Join the waitlist at usetemi.com and we'll email you when your state opens.
Reviewed by a board-certified physician licensed in California, Delaware, and Florida.
Last reviewed: April 17, 2026.
This page is educational and isn’t a substitute for advice from your prescribing physician. For questions about pricing, which states we serve, or how the flow works, see our FAQ.
Ready to refill your colchicine?
$15 flat fee. Any pharmacy. Usually reviewed within 24 hours.
Refill Colchicine